Oral Steroids

What are Oral Steroids (Chemically)?

Oral steroids are synthetic steroids that are similar to naturally occurring hormones. These are administered orally in the body. The most popular group of oral steroids comprises that include prednisolone, betamethasone, dexamethasone, hydrocortisone, methylprednisolone, and deflazacort etc. Oral steroids are intended to mimic the hormones released by your adrenal glands in reaction to stress and injury. as a result, when you take corticosteroids, the level of natural adrenal hormones increases above the normal level, which reduces inflammation. 

How Ingestible Steroids Work

The main impact of oral anabolic steroids is to stimulate the formation of erythropoietin, which increases the production of red blood cells (RBCs). As a result, oxygen flows more freely to the cells. When oxygen can circulate more freely, workouts are more productive. Better pumps and a powerful burst of power will occur, allowing you to lift more weight in the gym. 

According to the research, prednisolone, an oral steroid, directs the production of annexins, proteins that aid in muscle regeneration. Oral steroids or corticosteroids have a faster onset of performance advantages. Corticosteroids can help with the discomfort and inflammation of high-intensity exercise. These help break through painful, severe exertion and recover faster. 

Ingestible steroids can be used to reduce inflammation, suppress the immune response of a body, prevent DNA replication, and block the release of a molecule called histamine, which is released during an allergic reaction

How to Use Oral Steroids

Before you decide to buy oral steroids, it is important to learn about them first. 

The recommended drug dosage depends on the type of steroid and the disease for which it is administered. For short therapy courses, a somewhat high dose is frequently administered each day for a week or a few days and then rapidly terminated at the end of the course. If taken for more than three weeks,  must gradually reduce the dose. For those who need to take oral steroids for an extended period, a usual treatment plan is to take higher doses initially to reduce progressively and control symptoms. Then, the dose is usually gradually lowered to a lower daily dose that keeps the symptoms at bay. Depending on the condition, the length of treatment may vary. If the situation improves, the steroid medication may be gradually reduced.

Different Types of Oral Steroids

Some ingestible steroids can be used in combination to get better results. In human studies, dianabol and testosterone have been identified as the most potent and dominant anabolic steroids and the fastest muscle-building hormones. Bodybuilders have recently found success with the Dianabol combination such as —-. 

Other popular oral steroids include:

• Anadrol (oxymetholone) – an androgenic, anabolic steroid used to treat anemia, osteoporosis and promote weight gain and muscle growth.
• Anavar (oxandrolone) – promotes weight gain and helps reduces osteoporosis-induced pain.
• Arimidex (anastrozole) – a drug used to treat breast cancer in women by blocking steroidal conversion to estrogen. It also increases testosterone levels and is popular among bodybuilders.
• Aromasin (exemestane) – a drug to treat breast cancer in women.
• Nolvadex (tamoxifen) – used in breast cancer treatment. It also increases physical strength and muscle mass in men.
• Clomid (clomifene) – a drug to treat infertility in women. It is also frequently used with other anabolic steroids (such as dianabol, deca durabolin, and anavar) to build muscles.
• Winstrol (stanozolol) – a steroid to treat skin conditions. Winstrol also increase muscles mass and promotes recovery of muscle injury.
• Cytomel (triiodothyronine) – a prescription drug to treat thyroid hormone disorders. Cytomel increases the rate metabolism and energy conservation in a short amount of time.
• Turinabol (4-chlorodehydromethyltestosterone) – an anabolic steroid used as a performance enhancer.

Oral steroids can also be recommended as a replacement medication for those who don’t have enough of their natural steroids, such as in hypopituitarism and Addison’s disease. Steroids are usually taken with meals in the morning.

Things to Keep in Mind While Using Steroids

Oral steroids are potent anti-inflammatory medications that can help faster healing of injuries in athletes and bodybuilders. Overuse of the drugs, on the other hand, can result in substantial and sometimes paradoxical adverse effects, such as:

Negative effects

• The overuse of steroids leads to weight gain, muscle weakness, and thinning of the skin.
• Oral steroids can also increase susceptibility to infections, aggravating diabetes.
• It may cause acne, stomach irritation, and liver damage when used in a higher dose and for a prolonged period.

Positive effects

• Ingestible steroids work as an anti-inflammatory by inhibiting the formation of inflammation-causing prostaglandins, reducing the pain., redness, and swelling. Due to this feature of oral steroids, bodybuilders and athletes can get more out of it.
• Dexamethasone, an oral steroid, has been used by athletes to speed up their recovery from injuries and infections for many years.
• Corticosteroids act as a vasoconstrictor by blocking the inflammatory chemical histidine. As a result, mucus secretions are reduced, a significant cause of respiratory congestion.
• Oral Anabolic steroids can help you gain muscle and improve your athletic performance.

Final Thoughts 

Oral or ingestible steroids are powerful medicines that have a range of uses. Taken orally, they reduce inflammation, and reduce pain associated with arthritis, cancer, allergies, skin diseases and eye problems. Oral steroids are also an essential part of a bodybuilder’s routine. These wake up the body and increase circulation in the muscles. However, their use should be careful and done after a professional advice as they may have adverse effects. Just to be on the safe side, use oral steroids as per your doctor or instructor’s instructions. Before taking any steroids, consult your physician or pharmacist to get better outcomes.

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Frequently Asked Questions (FAQs)

Are oral steroids legal?

Yes, oral steroids are legal drugs.

Who can not take oral steroids?

People with serious infections can not take oral steroids because steroids can suppress our immune system.

I have high blood pressure. Can I take oral steroids?

Some oral steroids such as prednisone increase blood pressure. So consult your physician before taking any oral steroids. 

 References

Desta, Z., Nguyen, A., Flockhart, D., Skaar, T., Fletcher, R., Weinshilboum, R., et al. (2009). Antiestrogen pathway (aromatase inhibitor). Pharmacogenetics and Genomics, 19(7), 554–55.  https://doi.org/10.1097/FPC.0B013E32832E0EC1

Miller, A.B. (1991). Risk/benefit considerations of antiestrogen/estrogen therapy in healthy postmenopausal women. Prev, 20(1), 79-85. https://pubmed.ncbi.nlm.nih.gov/2008429/

Plourde, P. V., Dyroff, M., & Dukes, M. (1994). Arimidex®: A potent and selective fourth-generation aromatase inhibitor. Breast Cancer Research and Treatment. 30;103–111. https://doi.org/10.1007/BF00682745

Dank, M. (2002) The role of aromasin in the hormonal therapy of breast cancer. Pathology Oncology. 8;8. https://link.springer.com/article/10.1007/BF03033716